Bruker Avance 600 MHz NMR spectrometer

The NMR Bruker AVANCETM 600 MHz Spectrometer is mainly intended for biomedical research purposes. The magnet incorporates the key technologies of the UltraShieldTM Plus magnets. The AVANCETM III platform has three channels (SGU1, SGU2 and SGU3), the SGU1 to observe and decouple 1H and SGU2 and SGU3 for a frequency range between 109Ag and 31P. The magnet is equipped with 4 different probes, the 5 mm BBFO probe, 5 mm TXI 1H/13C/31P probe, HR-MAS 1H-13C-31P probe and a TCI CryoProbe Prodigy. The CryoProbe Prodigy is geared for handling either very low concentration samples or those with very high molecular weights and allows you to work at 0°C–80°C sample temperature range. The spectrometer is also equipped with a control temperature unit prepared to work at VT range (-50 °C to +50 °C).


  • UltraShieldTM Plus 9.4T magnet
  • 5 mm BBFOPLUS probe, optimized for X-nuclei direct observation in a frequency range between 31P and 15N. This probe has 2H "lock" and a z gradient, as well as automated tuning and matching (ATM).
  • 5 mm TXI probe, optimized for higher sensitivity 1H-nuclei observation. While the inner coil is optimized for 1H observation, the outer coil is optimized for decoupling of 13C and 31P. It has 2H "lock" channel and z gradient, and automated tuning and matching device (ATM).
  • 4 mm TXI HR-MAS probe, optimized for 1H-13C-31P observation. This probe has 2H "lock" channel and is configured with a Z-gradient aligned along the magic angle.
  • TCI CryoProbe Prodigy, uses nitrogen-cooled RF coils and preamplifiers for 1H, 2H and 13C, delivering a 2.5x 1H sensitivity boost. The probe is ATM compatible and has 2H "lock" channel and Z-gradient.
  • Control temperature unit (from -50 °C to 50 °C).


  • 1D spectroscopy: 1H, 13C, 31P, 29Si…
  • 2D correlation 1H-1H: COSY, NOESY, ROESY, TOCSY
  • 2D correlation 1H-X: HSQC, HMBC, HMQC, H2BC
  • Diffusion 1D, 2D DOSY

Applications In Biomedicine

Applications In Chemistry